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Selective determination of potential impurities in an active pharmaceutical ingredient using HPLC-SPE-HPLC

Eiichi Yamamoto1, Jun Niijima, Naoki Asakawa

  • 1Formulation Research, Pharmaceutical Science & Technology, Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba, Ibaraki 300-2635, Japan. e-yamamoto@hhc.eisai.co.jp

Journal of Pharmaceutical and Biomedical Analysis
|June 29, 2013
PubMed

Keywords:
ImpurityMulti-dimensional HPLCSelective determinationSolid-phase extractionSynthetic intermediate

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