Blink reflexes and magnetic resonance imaging in focal unilateral central trigeminal pathway demyelination

The electrically elicited blink reflex allows quantitative analysis of the corneal reflex which traverses the trigeminal and facial nerves and the brainstem. Two patients presenting with symptomatic unilateral trigeminal lesions are described, in whom the blink reflexes showed conduction block and slowing at predictable sites in the central pathways, and magnetic resonance imaging confirmed precisely the clinical and electrophysiological localisation.