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Updated: May 10, 2026

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
Published on: October 10, 2016
Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge Niphates sp
Nathalie Legrave1, Souhir Hamrouni-Buonomo, Maeva Dufies
1Chemistry Institute of Nice (ICN), UMR 7272 CNRS, Bioactive Molecules, University of Nice-Sophia Antipolis, ParcValrose, F-06108 Nice Cedex 02, France. nathalie.legrave@unice.fr
Abstract:
A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.
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