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Updated: May 10, 2026
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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[Renal functional state in patients with myocardial infarction]
Terapevticheskii Arkhiv
|July 2, 2013
Summary
Kidney dysfunction is common in myocardial infarction (MI) patients, linked to age and comorbidities. Early detection of renal filtration function aids treatment and improves outcomes.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Context:
- Myocardial infarction (MI) is a leading cause of mortality.
- Renal dysfunction is increasingly recognized as a significant comorbidity in cardiovascular disease.
- Understanding the interplay between MI and kidney function is crucial for patient management.
Purpose:
- To investigate the prevalence and characteristics of renal dysfunction in patients with acute myocardial infarction.
- To identify factors associated with worsening kidney function in MI patients.
- To assess the clinical implications of renal dysfunction in the context of MI.
Summary:
- Retrospective analysis of 670 acute coronary syndrome cases (369 male, 292 female, age 33-85) revealed moderate to severe kidney dysfunction in most patients.
- Worsening renal function correlated with older age, fewer males, and comorbidities like hypertension, heart failure, prior MI, and diabetes mellitus.
- Glomerular filtration rate (GFR) was estimated using the MDRD formula and patients were grouped based on GFR levels.
Impact:
- Kidney dysfunction plays a critical role in the development of multiple comorbidities in MI patients.
- Implementing GFR calculation in routine practice can help identify renal filtration issues promptly.
- Timely identification and treatment adjustments can potentially reduce adverse outcomes in MI patients with renal dysfunction.
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