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Updated: May 10, 2026
05:35
A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
[Anemia and gastrointestinal tract diseases]
Terapevticheskii Arkhiv
|July 2, 2013
Summary
Gastrointestinal diseases cause iron and vitamin B12 deficiencies, leading to anemia. Treating Helicobacter pylori infection can effectively manage refractory anemia in certain atrophic gastritis cases.
Area of Science:
- Gastroenterology
- Hematology
- Internal Medicine
Background:
- Gastrointestinal tract (GT) diseases are significant causes of iron and cyanobalamin (vitamin B12) deficiency anemias.
- Malabsorption and nutrient loss via the GT play a crucial role in developing these anemias.
- Current understanding of deficiency anemias in celiac disease and atrophic gastritis is reviewed.
Purpose of the Study:
- To review the pathogenesis of iron and cyanobalamin deficiency anemias linked to gastrointestinal diseases.
- To discuss current views on deficiency anemias in gluten-sensitive celiac disease and atrophic gastritis.
- To highlight the role of Helicobacter pylori infection treatment in managing refractory anemia.
Main Methods:
- Literature review of current views on the pathogenesis of deficiency anemias.
- Analysis of causes of iron and cyanobalamin deficiency anemias related to GT diseases.
- Inclusion of guidelines for Helicobacter pylori management.
Main Results:
- Malabsorption and nutrient loss are key factors in GT-related anemias.
- Autoimmune processes and H. pylori persistence are identified causes of atrophic gastritis leading to anemia.
- Treatment of H. pylori infection is effective for refractory anemia in specific atrophic gastritis forms.
Conclusions:
- Understanding the pathogenesis of deficiency anemias in GT diseases is crucial for effective management.
- Targeted treatment, such as H. pylori eradication, can resolve refractory anemias.
- Adherence to established guidelines for H. pylori management is recommended.
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