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Round cell liposarcoma metastatic to the heart
Behrooz Mottahedi1, Mehdi Asadi, Sara Amini
1Department of Cardiac Surgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Journal of Cardiac Surgery
|July 2, 2013
Summary
High-grade round cell liposarcoma, a rare soft tissue tumor, can metastasize to the heart. This case highlights successful treatment of cardiac liposarcoma with surgery and radiotherapy, showing no recurrence after 12 months.
Area of Science:
- Oncology
- Cardiovascular Pathology
- Surgical Oncology
Background:
- Myxoid liposarcoma is a malignant soft tissue neoplasm primarily affecting adults.
- Cardiac involvement by liposarcoma is exceptionally rare, posing diagnostic and therapeutic challenges.
- High-grade round cell liposarcoma represents an aggressive subtype with metastatic potential.
Observation:
- A 50-year-old female presented with high-grade round cell liposarcoma originating in the left knee.
- Metastatic disease was identified within the right heart chambers, specifically the right atrium and extending into the right ventricle.
- The cardiac tumor required surgical resection followed by adjuvant radiotherapy.
Findings:
- Complete surgical resection of the cardiac liposarcoma was achieved.
- Adjuvant radiotherapy was administered post-operatively.
- A 12-month follow-up demonstrated no evidence of recurrent cardiac disease, indicating treatment efficacy.
Implications:
- This case underscores the importance of considering rare metastatic sites, such as the heart, in patients with aggressive soft tissue sarcomas.
- Multidisciplinary management involving surgical oncology and radiation oncology is crucial for optimal outcomes.
- Successful treatment of cardiac liposarcoma suggests that aggressive therapeutic approaches can lead to favorable prognoses.
