Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development

Qingjie Ding1, Zhuming Zhang, Jin-Jun Liu

  • 1Discovery Chemistry, ‡Discovery Technologies, §Discovery Oncology, ∥Non-Clinical Development, Roche Research Center, Hoffmann-La Roche, Inc. , 340 Kingsland Street, Nutley, New Jersey 07110, United States.