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Ratiometric fluorescent probes for detection of intracellular singlet oxygen

Dayoung Song1, Somin Cho, Yejee Han

  • 1Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, Korea.

Organic Letters
|July 2, 2013
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...