What's the fuss over human frontal lobe evolution?
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Updated: May 10, 2026

Electroporation of Sliced Human Cortical Organoids for Studies of Gene Function
Published on: November 29, 2024
Chet C Sherwood1, Jeroen B Smaers
1Department of Anthropology, The George Washington University, Washington, DC 20052, USA. sherwood@gwu.edu
Abstract:
Evolutionary neuroscientists seek to understand what makes the human neocortex special aside from its extraordinary expansion. New analyses find that the frontal lobes of humans are not relatively enlarged given our species' brain size. But are statistical cut-offs masking biologically meaningful changes in the size of the human prefrontal cortex?
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