Related Experiment Video
Updated: May 10, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
Published on: September 8, 2023
[Bone micro-structural changes following osteoporotic drug treatment]
1Bone & Joint Surgery, Seirei Hamamatsu General Hospital, Japan.
Abstract:
Osteoporotic drugs improve bone mechanical integrity by increasing bone mass and also by improving bone structure and quality, where controlling bone metabolism. Changes in trabecular microstructure can be detected since early period after starting drug treatment. Effects on bone metabolism of anti-resorptive agent of bisphosphonates are totally opposite from those of anabolic agent of teriparatide, however these different drug treatments results in the improvement of trabecular microstructure as well.
More Related Videos
08:53Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
Published on: January 1, 2017
04:24Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography
Published on: November 22, 2017
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling
Bone Remodeling and Repair
Osteoclasts in Bone Remodeling
Bone Structure
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...