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Updated: May 10, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Current management considerations for the incidentally detected small renal mass
David D Buethe1, Philippe E Spiess
1Genitourinary Oncology Program, Moffitt Cancer Center, Tampa, FL 33612, USA.
Nephron-sparing treatments are effective for small renal masses, offering oncologic efficacy comparable to radical nephrectomy. Options like partial nephrectomy, active surveillance, and thermal ablation should be discussed with patients.
Area of Science:
- Urology
- Oncology
- Nephrology
Background:
- Small renal masses are increasingly detected incidentally.
- Nephron-sparing treatments for small renal masses are underutilized.
- There is a downward stage migration in renal cell carcinoma detection.
Purpose of the Study:
- To review current paradigms in small renal mass management.
- To evaluate the efficacy and safety of various treatment options.
- To highlight the importance of patient-centered decision-making.
Main Methods:
- Review of historical publications representing accepted paradigms.
- Contemporary literature search in PubMed (human studies, English).
- Inclusion of clinical trials, meta-analyses, RCTs, and practice guidelines; augmented by retrospective trials.
Main Results:
- Partial nephrectomy is oncologically equivalent and safe compared to radical nephrectomy.
- Minimally invasive partial nephrectomy (laparoscopic, robotic) is as effective as open techniques.
- Active surveillance and thermal ablation are viable for selected patients, supported by retrospective data.
Conclusions:
- Management of small renal masses involves multiple therapeutic options.
- Individualized discussion with patients is crucial for treatment selection.
- Shared decision-making ensures optimal patient outcomes.
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