Painless angioleiomyoma of the first web space of the hand

Angioleiomyoma is a benign dermal or subcutaneous tumor originating from the tunica media of small veins and arteries, and rarely occurs in the hand. Because of its non-specific imaging features, a definite preoperative diagnosis is quite difficult. We present an unusual case of angioleiomyoma arising in the first web space of the right hand of a 56-year-old male. Physical examination showed a 3-cm, elastic-soft, mobile, non-tender mass. Magnetic resonance imaging (MRI) revealed a well-demarcated, subcutaneous, soft tissue mass with iso- to slightly high signal intensity relative to skeletal muscle on T1-weighted sequences and heterogenous high signal intensity with scattered foci of low signal intensity on T2-weigthed sequences. Contrast-enhanced fat-suppressed T1-weighted sequences demonstrated heterogenous, strong enhancement throughout the mass. There was no vascular structure closely abutting the mass. Simple excision of the mass was performed, and the histology was characteristic of an angioleiomyoma. The patient had no evidence of local recurrence within four months of follow-up. Angioleiomyoma should be considered in the differential diagnosis of a well-defined, oval soft tissue mass in the first web space of the hand even when an adjacent tortuous vascular structure is not seen on MRI.