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Updated: May 10, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Bilateral acute depigmentation of the iris (BADI): first reported case in Brazil
Heloisa Andrade Maestrini1, Angela Andrade Maestrini, Danuza de Oliveira Machado
1Glaucoma Service, Oculare Ophthalmology Center, Belo Horizonte, Brazil. heloisa.maestrini@gmail.com
Abstract:
Bilateral acute depigmentation of the iris (BADI) is a recently described entity characterized by acute onset of pigment dispersion in the anterior chamber, depigmentation of the iris, and heavy pigment deposition in the anterior chamber angle. Involvement is always bilateral, simultaneous, and symmetrical. We report the case of a 61-year-old man who presented with bilateral ocular pain, red eyes, and severe photophobia. Examination revealed a dense Krukenberg spindle, heavy pigment dispersion in the anterior chamber, extensive transillumination iris defects, and a heavy pigment deposition in the trabecular meshwork bilaterally. Intraocular pressure increased to 48 mmHg in both eyes. The patient received topical steroids, maximum hypotensive treatment and oral valacyclovir. Intraocular pressure gradually decreased throughout the second and third months, and medications were gradually tapered. The time to complete resolution of pigment dispersion was 18 weeks. Visual acuity and visual fields remained normal, but the photophobia was permanent.
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