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Related Concept Videos

Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
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Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
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Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.

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Updated: May 10, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

A forgotten lethal psychosis: a case report.

Diego Hidalgo Mazzei1, Sergio Martín Rodriguez2, Hipólito Pérez Moltó2

  • 1Department of Psychiatry, Institut Clínic de Neurociències, Hospital Clínic, Barcelona, Spain. dahidalg@clinic.ub.es.

European Child & Adolescent Psychiatry
|July 2, 2013
PubMed
Summary
This summary is machine-generated.

Homocystinuria, an inborn error of metabolism, can cause severe health issues. This case highlights a rare presentation of psychosis as the first symptom, leading to a fatal outcome in a young patient.

Keywords:
AdolescentHomocystinuriaLethalPsychosis

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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

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Published on: September 20, 2018

Area of Science:

  • Biochemistry
  • Genetics
  • Neurology

Background:

  • Homocystinuria is an inherited metabolic disorder caused by cystathionine β-synthase deficiency.
  • It leads to elevated plasma homocysteine and potential severe health complications if untreated.

Observation:

  • A 17-year-old male presented with a first episode of psychosis.
  • His homocystinuria due to cystathionine β-synthase deficiency was previously undiagnosed.

Findings:

  • Psychiatric disorders affect nearly 50% of individuals with homocystinuria.
  • Psychotic disorders are an infrequent initial manifestation of this condition.

Implications:

  • This case underscores the importance of considering metabolic disorders in psychiatric presentations.
  • Early diagnosis and treatment of homocystinuria are crucial to prevent severe outcomes, including psychiatric manifestations and mortality.