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Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
09:39

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

Cramps and small-fiber neuropathy

Glenn Lopate1, Elizabeth Streif, Matthew Harms

  • 1Department of Neurology, Division of Neuromuscular Disease, Washington University School of Medicine, Campus Box 8111, 660 South Euclid Avenue, St. Louis, Missouri 63110, USA. lopateg@neuro.wustl.edu

Muscle & Nerve
|July 2, 2013
PubMed
Summary

Sixty percent of patients experiencing muscle cramps without nerve complaints were found to have small-fiber neuropathy (SFN). This suggests SFN may cause cramps through inflammation from damaged small nerves exciting intramuscular nerves.

Keywords:
muscle crampsperipheral nervous system diseaseskin biopsysmall-fiber neuropathyunmyelinated nerve fibers

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