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Updated: May 10, 2026
06:55
Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
Osler-Weber-Rendu syndrome during pregnancy
1Obstetrics Gynaecology Department, Centro Hospitalar do Porto-Maternidade Júlio Dinis, Porto, Portugal. dr.inocencio@gmail.com
BMJ Case Reports
|July 2, 2013
Summary
Osler-Weber-Rendu syndrome, a rare vascular disorder, can cause severe bleeding. This case study shows a pregnant woman with the syndrome experienced a normal pregnancy and delivery, with manageable symptoms.
Area of Science:
- Vascular Medicine
- Genetics
- Obstetrics
Background:
- Osler-Weber-Rendu syndrome (Hereditary Hemorrhagic Telangiectasia) is a rare genetic disorder causing abnormal blood vessel formation.
- Angioma rupture in this condition can lead to severe, difficult-to-control hemorrhages, with recurrent epistaxis as a primary symptom.
- Pregnancy may present increased risks for patients with Osler-Weber-Rendu syndrome due to potential complications.
Observation:
- A case of a pregnant woman diagnosed with Osler-Weber-Rendu syndrome is presented.
- The patient experienced frequent epistaxis and microcytic hypochromic anemia, which responded to oral iron therapy.
- Despite the underlying condition, her pregnancy progressed without significant obstetric complications.
Findings:
- The pregnant patient with Osler-Weber-Rendu syndrome maintained a normal pregnancy.
- She underwent a vaginal delivery without complications during the puerperium.
- Management of epistaxis and anemia was successfully achieved with standard treatments.
Implications:
- This case suggests that pregnancy in women with Osler-Weber-Rendu syndrome can be managed successfully with careful monitoring.
- It highlights the importance of symptomatic treatment for epistaxis and anemia in affected pregnant individuals.
- Further research may elucidate optimal management strategies for Osler-Weber-Rendu syndrome during pregnancy.
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