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Related Concept Videos

Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Cellular Adaptation IV: Dysplasia and Metaplasia01:24

Cellular Adaptation IV: Dysplasia and Metaplasia

DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...

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Related Experiment Video

Updated: May 10, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
10:26

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

[Laryngeal papillomatosis: problem update].

V M Svistushkin, D M Mustafaev

    Vestnik Otorinolaringologii
    |July 2, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Laryngeal papillomatosis is caused by the human papilloma virus (HPV) and involves abnormal cell growth. Effective diagnosis uses polymerase chain reaction and in situ hybridization, with ongoing research into advanced treatments.

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    Learning Modern Laryngeal Surgery in a Dissection Laboratory
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    Learning Modern Laryngeal Surgery in a Dissection Laboratory

    Published on: March 18, 2020

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    Last Updated: May 10, 2026

    RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
    10:26

    RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

    Published on: March 11, 2014

    Learning Modern Laryngeal Surgery in a Dissection Laboratory
    07:30

    Learning Modern Laryngeal Surgery in a Dissection Laboratory

    Published on: March 18, 2020

    Area of Science:

    • Otolaryngology
    • Virology
    • Oncology

    Context:

    • Laryngeal papillomatosis is a rare condition characterized by the growth of benign tumors in the larynx.
    • Etiology, pathogenesis, diagnostics, and treatment strategies require continuous evaluation.

    Purpose:

    • To analyze current data on the causes, development, diagnosis, and treatment of laryngeal papillomatosis.
    • To highlight the role of cell proliferation mechanisms and human papilloma virus (HPV) in the disease's pathogenesis.

    Summary:

    • Human papilloma virus (HPV) is the primary etiological agent, effectively detected using polymerase chain reaction (PCR) and in situ hybridization.
    • Current treatment modalities include surgical interventions (endoscopic, laser), adjuvant pharmaceutical therapies (e.g., cidofovir, indole-3-carbinol), and emerging vaccination methods.
    • Advanced diagnostic and prognostic criteria are anticipated from molecular biology, morphology, and immunology advancements.

    Impact:

    • Provides a comprehensive overview of laryngeal papillomatosis management.
    • Identifies key diagnostic markers and therapeutic approaches.
    • Suggests future research directions for improved patient outcomes in laryngeal papillomatosis.