Related Experiment Video
Updated: May 10, 2026

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
Published on: November 11, 2013
Gender differences in heroin users receiving methadone maintenance therapy in Taiwan
Huang-Chi Lin1, Yu-Ping Chang, Peng-Wei Wang
1Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
This study reveals significant gender differences in individuals receiving Methadone Maintenance Treatment (MMT). Female heroin users often face greater burdens, including unemployment and trauma, compared to men.
Area of Science:
- Addiction Medicine
- Public Health
- Gender Studies in Health
Background:
- Heroin use and its treatment present unique challenges.
- Understanding gender-specific factors in substance use disorders is crucial for effective treatment.
- Methadone Maintenance Treatment (MMT) is a key intervention for opioid use disorder.
Purpose of the Study:
- To investigate and delineate gender disparities among heroin users initiating MMT.
- To identify demographic, substance use, and psychosocial differences between male and female patients.
Main Methods:
- Comparative analysis of male and female heroin users.
- Examination of age at initiation of heroin and other substance use.
- Assessment of employment status, family history of substance use, and presence of child-raising burden and trauma.
Main Results:
- Female heroin users were younger, more frequently unemployed, and initiated heroin use earlier.
- Women reported higher rates of methamphetamine use, earlier initiation of methamphetamine, child-raising burdens, and trauma history.
- Men showed higher rates of betel quid use and earlier initiation of alcohol, nicotine, and betel quid.
Conclusions:
- Gender significantly influences the profile of heroin users entering MMT.
- Female patients present with complex psychosocial challenges, including trauma and caregiving responsibilities, necessitating tailored treatment approaches.
- Distinct patterns of polysubstance use initiation exist between genders, impacting treatment planning.
Related Concept Videos
Therapeutic Drug Monitoring: Affecting Factors
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Drug Abuse and Addiction: Pharmacological Phenomena
Drug Dependence
Analgesia and Pain Management
