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Updated: May 10, 2026

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
Published on: August 23, 2019
MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
Hilda Samimi1, Majid Zaki Dizaji, Mohsen Ghadami
1Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, 5th floor, Dr, Shariati Hospital, North Kargar Ave, Tehran, Iran. v.haghpanah@gmail.com.
Abstract:
miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18-25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper.
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