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Optic nerve involvement associated with the multiple evanescent white-dot syndrome.
D G Dodwell1, L M Jampol, M Rosenberg
1Department of Ophthalmology, Northwestern University Medical School, Chicago, IL.
Ophthalmology
|July 1, 1990
Summary
Multiple evanescent white-dot syndrome (MEWDS) can mimic primary optic nerve disease. Early diagnosis is crucial for managing this condition, which presents with optic nerve dysfunction and visual field defects.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
Background:
- Primary optic nerve disease presents with various symptoms affecting vision.
- Accurate diagnosis is essential for appropriate patient management and prognosis.
Observation:
- Five patients with optic nerve disease symptoms were diagnosed with MEWDS.
- Clinical signs included disc edema, central vision loss, and visual field defects.
Findings:
- MEWDS diagnosis was challenging due to subtle white spot presentations.
- Optic nerve dysfunction was a key feature in all diagnosed patients.
Implications:
- MEWDS should be considered in young, healthy individuals with optic nerve dysfunction.
- This syndrome can present unilaterally or bilaterally, requiring careful evaluation.