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Update on pediatric photosensitivity disorders
1Department of Dermatology, Johns Hopkins University, Baltimore, Maryland 21287, USA. agrossb2@jhmi.edu
Insights
Pediatric photosensitivity disorders, though rare, encompass diverse causes. Diagnosis can be achieved through an algorithmic approach, guiding further management.
Area of Science:
- Pediatric Dermatology
- Photosensitivity Disorders
- Genodermatoses
Background:
- Photosensitive dermatoses can manifest in children, originating from various causes.
- These include primary immunologically mediated conditions and inherited genetic or metabolic disorders.
Purpose of the Study:
- To review key features of pediatric photosensitivity disorders.
- To familiarize pediatric practitioners with symptoms and extracutaneous findings.
Main Methods:
- Literature review of recent advances in pediatric photosensitivity.
- Focus on diagnostic approaches and management strategies.
Main Results:
- Recent significant advances in the field of pediatric photosensitivity are limited.
- Ongoing research continues to uncover genetic underpinnings and mechanisms of photosensitivity.
Conclusions:
- A broad differential diagnosis exists for pediatric photosensitivity.
- An algorithmic diagnostic approach aids in identifying specific disorders and guiding management.
Purpose Of Review:
Although rare in the pediatric population, photosensitive dermatoses may begin prior to adulthood. The causes of photosensitivity are diverse, ranging from primary, immunologically mediated disorders of photosensitivity to inherited genetic or metabolic disorders. This review will highlight the key features of these disorders to familiarize the pediatric practitioner with their symptoms and any associated extracutaneous clinical or laboratory findings that may accompany them.
Recent Findings:
New developments in the field of pediatric photosensitivity have been scant over recent years. While mechanisms of photosensitivity and genetic underpinnings associated with various conditions such as xeroderma pigmentosum continue to be uncovered, the literature on disorders of photosensitivity has been otherwise without many recent significant advances.
Summary:
Although the differential diagnosis of pediatric photosensitivity disorders is broad, it is often possible to establish the diagnosis by following an algorithmic approach. Once the correct diagnosis is rendered, this will guide any further workup that needs to be performed as well as specific management strategies.
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