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Goal-dependent dissociation of visual and prefrontal cortices during working memory
Sue-Hyun Lee1, Dwight J Kravitz, Chris I Baker
1Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA. sue-hyun.lee@nih.gov
None:
To determine the specific contribution of brain regions to working memory, human participants performed two distinct tasks on the same visually presented objects. During the maintenance of visual properties, object identity could be decoded from extrastriate, but not prefrontal, cortex, whereas the opposite held for nonvisual properties. Thus, the ability to maintain information during working memory is a general and flexible cortical property, with the role of individual regions being goal-dependent.
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