Related Experiment Video

Updated: May 10, 2026

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
07:33

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

Hofmeister salts recover a misfolded multiprotein complex for subsequent structural measurements in the gas phase

Linjie Han1, Brandon T Ruotolo

  • 1Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA.

Angewandte Chemie (International Ed. in English)
|July 3, 2013
PubMed
Abstract

No abstract available in PubMed .

Keywords:
circular dichroismdifferential scanning calorimetryion mobilitymass spectrometryprotein misfolding

More Related Videos

Analyzing Large Protein Complexes by Structural Mass Spectrometry15:35

Analyzing Large Protein Complexes by Structural Mass Spectrometry

Published on: June 19, 2010

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis16:40

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Published on: July 31, 2010

Related Concept Videos

Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...