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Updated: May 10, 2026
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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
Subretinal angiostrongyliasis-induced optic neuritis
Suthasinee Sinawat1, Yosanan Yospaiboon, Supat Sinawat
1Vitreoretinal Unit, Department of Ophthalmology, Khon Kaen University, Khon Kaen, Thailand.
Clinical Ophthalmology (Auckland, N.Z.)
|July 3, 2013
Summary
A rare case of ocular angiostrongyliasis occurred in a Thai male due to Angiostrongylus cantonensis infection. Treatment involved laser ablation, steroids, and antiparasitic drugs, with minimal visual improvement.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Parasitology
Background:
- Ocular manifestations of parasitic infections are rare.
- Angiostrongylus cantonensis is a known cause of eosinophilic meningitis, with eye involvement being exceptionally uncommon.
Observation:
- A 27-year-old male presented with vision loss and a subretinal larva.
- The larva exhibited movement and created tracks within the subretinal space.
- Diagnostic tests revealed a relative afferent pupillary defect and delayed visual evoked potentials, suggesting optic neuritis.
Findings:
- A motile Angiostrongylus cantonensis larva was identified in the subretinal space.
- Laser ablation of the larva was performed, followed by oral prednisolone and albendazole.
- The patient showed slight visual acuity improvement post-treatment.
Implications:
- Ocular angiostrongyliasis is a rare condition, with only 1.1% of cases involving eye identification of the Angiostrongylus cantonensis larva.
- Optic neuritis in this context may result from mechanical damage or inflammation.
- While treatment can be initiated, visual outcomes are often limited, highlighting the importance of early diagnosis and management.
