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Paecilomyces variotii as an Emergent Pathogenic Agent of Pneumonia

Bruna Steiner1, Valerio R Aquino, Alessandra A Paz

  • 1Infectious Diseases Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2350, Porto Alegre, RS 90035-903, Brazil.

Case Reports in Infectious Diseases
|July 3, 2013
PubMed

Insights

Pneumonia caused by Paecilomyces variotii is rare, especially in immunocompromised patients. This study details a case in a lymphoma patient post-transplant and reviews similar documented infections.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Hematology

Background:

  • Paecilomyces variotii is a fungus found in air and food.
  • It is associated with various human infections.
  • Pneumonia caused by this fungus is infrequently documented.

Purpose of the Study:

  • To report a rare case of Paecilomyces variotii pneumonia.
  • To describe the clinical presentation in an immunocompromised patient.
  • To review existing literature on Paecilomyces variotii pneumonia.

Main Methods:

  • Case report of a 48-year-old patient with refractory lymphoma.
  • Allogenic hematopoietic cell transplantation.
  • Literature review of published pneumonia cases caused by Paecilomyces variotii.

Main Results:

  • The patient developed pneumonia post-hematopoietic cell transplantation.
  • Paecilomyces variotii was identified as the causative agent.
  • The review identified a limited number of similar cases.

Conclusions:

  • Paecilomyces variotii can cause pneumonia in immunocompromised individuals, particularly after transplantation.
  • Early diagnosis and treatment are crucial for managing this rare fungal infection.
  • Further research is needed to understand the full spectrum of Paecilomyces variotii infections.

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