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[Problem of a comorbidity of arterial hypertension and acid-dependent diseases]

O V Khlynova, A V Tuev, L N Beresneva

    Terapevticheskii Arkhiv
    |July 4, 2013
    PubMed

    Insights

    This review examines arterial hypertension (AH) and acid-dependent diseases (ADD), highlighting their shared risk factors, clinical presentations, and diagnostic challenges. It explores therapeutic strategies for managing concurrent AH and ADD, focusing on gastrointestinal health.

    Area of Science:

    • Internal Medicine
    • Gastroenterology
    • Cardiology

    Context:

    • Arterial hypertension (AH) and acid-dependent diseases (ADD) are highly prevalent conditions.
    • Their co-occurrence presents unique clinical challenges and diagnostic complexities.
    • Understanding the interplay between AH and ADD is crucial for effective patient management.

    Purpose:

    • To review the literature on the comorbidity of arterial hypertension and acid-dependent diseases.
    • To analyze the prevalence, etiology, pathogenesis, and clinical features of these concurrent conditions.
    • To discuss diagnostic difficulties and therapeutic approaches for patients with both AH and ADD.

    Summary:

    • The review synthesizes data on the shared etiological and pathogenetic factors of AH and ADD.
    • It details the clinical, morphological, and hemodynamic characteristics of patients with concurrent AH and gastrointestinal diseases.
    • Specific features of autonomic regulation, diurnal blood pressure, and central hemodynamics in this comorbidity are examined.

    Impact:

    • Provides insights into the complex relationship between hypertension and acid-related gastrointestinal disorders.
    • Informs clinical practice regarding the diagnosis and management of patients with comorbid AH and ADD.
    • Highlights the importance of considering gastrointestinal effects in antihypertensive therapy for patients with ADD.

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