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Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression

Tomoyasu Isobe1, Soken-Nakazawa J Song, Prabha Tiwari

  • 1Immuno-Medical Science, Division of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

FEBS Letters
|July 4, 2013
PubMed

Keywords:
5-aza-2′-deoxycytidine5-aza-dCAIDCOBRAChIPDemethylationGadd45H-RasHSV-TKHarvey rat sarcoma viral oncogene homologNF-κBPGCsPax5RT-PCRSV40TNFαTSSchromatin immunoprecipitationcombined bisulfite restriction analysisgrowth arrest and DNA damage inducible protein 45herpes simplex virus-thymidine kinasenuclear factor-κBpaired box gene 5primordial germ cellsqRT-PCRquantitative RT-PCRreverse transcription-polymerase chain reactionsimian vacuolating virus 40transcription start sitetumor necrosis factor α

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