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Updated: May 10, 2026

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Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Vaginal cuff closure with absorbable bidirectional barbed suture during total laparoscopic hysterectomy
Stefano Bogliolo1, Chiara Nadalini, Anna Daniela Iacobone
1Department of Obstetrics and Gynaecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Obstetrics and Gynaecology, San Paolo Hospital, Savona, Italy.
Summary
Double barbed sutures for vaginal cuff closure during laparoscopic hysterectomy are safe and effective, significantly reducing operative times compared to traditional methods.
Area of Science:
- Gynecological Surgery
- Minimally Invasive Procedures
- Surgical Suturing Techniques
Background:
- Hysterectomy is a common gynecological procedure.
- Minimally invasive approaches offer patient benefits and cost reductions.
- Vaginal cuff closure is a critical step in hysterectomy.
Purpose of the Study:
- To evaluate the efficacy and safety of double barbed sutures for vaginal cuff closure.
- To compare double barbed sutures with traditional interrupted sutures in total laparoscopic hysterectomy.
- To assess the impact on operative time and complication rates.
Main Methods:
- Retrospective cohort study of 88 patients undergoing total laparoscopic hysterectomy.
- Comparison of vaginal cuff closure using traditional polycolic acid sutures (n=40) versus bidirectional barbed sutures (Quill SRS™, n=48).
- Data collected on operative times, vaginal cuff dehiscence, bleeding, and infection rates.
Main Results:
- No significant differences in vaginal cuff dehiscence, bleeding, or infection between the two suture groups.
- Bidirectional barbed sutures resulted in a significant reduction in operative times.
- The Quill SRS™ device demonstrated safety and tolerability.
Conclusions:
- Bidirectional barbed sutures (Quill SRS™) provide a safe and effective method for vaginal cuff closure in total laparoscopic hysterectomy.
- This technique offers a significant advantage by reducing operative times.
- The procedure is well-tolerated by patients, maintaining safety profiles comparable to traditional methods.