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Related Concept Videos

Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
Pulse01:05

Pulse

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Special considerations while measuring pulse01:13

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
Regulation of Pulse01:20

Regulation of Pulse

Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.
Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...

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Related Experiment Video

Updated: May 10, 2026

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
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Rotary pumps and diminished pulsatility: do we need a pulse?

Kevin G Soucy1, Steven C Koenig, Guruprasad A Giridharan

  • 1Division of Thoracic and Cardiovascular Surgery, University of Louisville, Louisville, Kentucky 40202, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 4, 2013
PubMed
Summary

Continuous flow ventricular assist devices (CVADs) offer advantages but may cause complications due to reduced pulsatility. Developing new control algorithms for CVADs could mitigate risks and improve heart recovery.

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Area of Science:

  • Cardiovascular Engineering
  • Medical Device Technology
  • Heart Failure Management

Background:

  • Ventricular assist devices (VADs) are crucial for heart failure (HF) patients, serving as a bridge to transplant or destination therapy (DT).
  • Continuous flow VADs (CVADs) are increasingly used due to their smaller size and improved reliability compared to pulsatile flow VADs (PVADs).
  • CVADs have been linked to adverse events like gastrointestinal bleeding and hemorrhagic strokes, with diminished arterial pressure pulsatility being a suspected cause.

Purpose of the Study:

  • To investigate the debate surrounding the potential link between reduced pulsatility from CVADs and associated complications.
  • To explore the uncertainty in current research regarding CVADs for DT due to device variations and inconsistent pulsatility measurements.
  • To highlight the emerging interest in developing advanced control algorithms for CVADs to enhance pulsatility and mitigate adverse events.

Main Methods:

  • Review of existing studies comparing pulsatile flow VAD (PVAD) and continuous flow (CF) support.
  • Analysis of factors contributing to conflicting findings, including device operation, support duration, and pulsatility quantification.
  • Exploration of potential benefits of novel control strategies for CVAD therapy.

Main Results:

  • Conflicting findings exist in studies comparing PVAD and CF support, with relevance to DT remaining uncertain.
  • Variations in device operation, support duration, and pulsatility measurement criteria complicate direct comparisons.
  • Current research indicates a need for further investigation into the effects of pulsatility on CVAD-related complications.

Conclusions:

  • Developing control algorithms for CVADs to increase pulsatility is a promising strategy to reduce adverse events.
  • Optimized control strategies may also enhance myocardial recovery and facilitate successful weaning from mechanical circulatory support.
  • Further research is needed to fully understand and address the implications of pulsatility in CVAD therapy for heart failure patients.