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Updated: May 10, 2026

Decellularized Apple-Derived Scaffolds for Bone Tissue Engineering In Vitro and In Vivo
09:49

Decellularized Apple-Derived Scaffolds for Bone Tissue Engineering In Vitro and In Vivo

Published on: February 23, 2024

Biomaterials for tissue engineering.

Esther J Lee1, F Kurtis Kasper, Antonios G Mikos

  • 1Department of Bioengineering, Rice University, MS 142, P.O. Box 1892, Houston, TX, 77251-1892, USA.

Annals of Biomedical Engineering
|July 4, 2013
PubMed
Summary
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Biomaterials are key to tissue engineering, providing scaffolds for bone and cartilage regeneration. This review covers current materials, design factors, and future directions for the osteochondral interface.

Area of Science:

  • Biomaterials science
  • Tissue engineering
  • Regenerative medicine

Background:

  • Biomaterials are crucial for tissue engineering, mimicking the extracellular matrix to promote cell growth and tissue repair.
  • Bone and cartilage have distinct properties but interface at the osteochondral region.
  • Understanding biomaterials for these tissues is vital for regenerative strategies.

Purpose of the Study:

  • To provide an overview of current biomaterials used in bone and cartilage tissue engineering.
  • To discuss key design considerations for these biomaterials.
  • To explore future prospects in the field of osteochondral regeneration.

Main Methods:

  • Literature review of current biomaterials for bone and cartilage applications.
  • Analysis of design considerations for biomaterial development.

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Last Updated: May 10, 2026

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  • Discussion of future research trends and challenges.

    • Main Results:

    • Identified various biomaterials currently used for bone and cartilage regeneration.
    • Highlighted critical design factors influencing biomaterial performance.
    • Outlined potential future advancements in biomaterial-based therapies.

    Conclusions:

    • Biomaterials play a fundamental role in advancing bone and cartilage tissue engineering.
    • Careful consideration of material properties and design is essential for successful regeneration.
    • Continued research promises innovative solutions for osteochondral defects.