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Related Experiment Video

Updated: May 10, 2026

Transvaginal Mesh Insertion in the Ovine Model
10:32

Transvaginal Mesh Insertion in the Ovine Model

Published on: July 27, 2017

Mesh pullout force: comparative study of different deployment techniques in a sheep model.

Menachem Alcalay1, Miron Livneh, Naama Marcus Braun

  • 1Department of Obstetrics & Gynecology, Chaim Sheba Medical Center, Ramat Gan, 52621, Israel, malcalay@netvision.net.il.

International Urogynecology Journal
|July 4, 2013
PubMed
Summary

The EndoFast Reliant system offers superior initial mesh fixation for pelvic organ prolapse repair compared to traditional methods. This enhanced pullout force advantage diminishes by 15 days post-surgery.

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Area of Science:

  • Biomedical Engineering
  • Surgical Innovation
  • Pelvic Floor Reconstruction

Background:

  • Pelvic organ prolapse (POP) repair often involves mesh implantation.
  • Mesh fixation strength is crucial for successful surgical outcomes.
  • Current fixation methods include trocar-based techniques and newer soft-tissue fasteners.

Purpose of the Study:

  • To compare the mesh-to-tissue pullout force between the EndoFast Reliant system and traditional trocar-based fixation methods (tissue tunnel, tissue pocket).
  • To evaluate the mechanical properties of mesh fixation over time in a preclinical model.

Main Methods:

  • A sheep model was used to assess three mesh attachment methods: EndoFast Reliant, tissue pocket, and tissue tunnel.
  • Pullout force was measured at multiple time points post-surgery (0, 3, 7, 15, 30, and 45 days).

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  • Statistical analysis included one-way ANOVA and a general linear model for repeated measures.

    • Main Results:

    • The EndoFast Reliant system demonstrated significantly higher pullout force in the immediate postoperative period (0-3 days) compared to trocar-based methods.
    • This difference in pullout force was not statistically significant by day 7.
    • Mesh pullout force increased in all groups, leading to mesh tearing by day 15, with similar forces across all fixation methods.

    Conclusions:

    • The EndoFast Reliant system provides superior immediate mechanical stability for mesh fixation in POP repair.
    • The enhanced fixation strength of EndoFast Reliant compared to trocar-based techniques is most pronounced in the early postoperative phase.
    • This advantage in pullout force diminishes by 15 days, suggesting comparable long-term fixation across methods studied.