Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-omics biomarkers of endothelial dysregulation preceding chronic lung allograft dysfunction: A prospective cohort study.

PLoS medicine·2026
Same author

A Perspective Summary of the ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD).

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD): Definition, Etiology, Diagnostic and Therapeutic Approaches, and Research Priorities.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

What factors are associated with work after cardiothoracic transplant? A systematic review.

Transplantation reviews (Orlando, Fla.)·2026
Same author

Improving access without compromise: Policy reform and outcomes in pediatric lung.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Multi-center open-label tacrolimus inhalation powder trial evaluating safety, tolerability, efficacy, and pharmacokinetics in adult lung transplant recipients with significant renal impairment.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

Monographic Issue on New Concepts in Acute Exacerbations of COPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Bidirectional Clinical Interactions among Exacerbations and Comorbidities in COPD: A Narrative Review.

Seminars in respiratory and critical care medicine·2026
Same journal

Radiological Approach to Severe Respiratory Infections and Pulmonary Complications in Immunocompromised Patients.

Seminars in respiratory and critical care medicine·2026
Same journal

Two Sides of the Same Smoke: Decoding Respiratory Bronchiolitis-Associated Interstitial Lung Disease and Alveolar Macrophage Pneumonia.

Seminars in respiratory and critical care medicine·2026
Same journal

Role of Vaccination in the Prevention of ECOPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Pharmacological Treatment of AECOPD New Perspectives.

Seminars in respiratory and critical care medicine·2026
See all related articles

Related Experiment Video

Updated: May 10, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Donor selection and management.

Gregory I Snell1, Miranda Paraskeva, Glen P Westall

  • 1Lung Transplant Service, Alfred Hospital and Monash University, Melbourne, Australia. g.snell@alfred.org.au

Seminars in Respiratory and Critical Care Medicine
|July 4, 2013
PubMed
Summary
This summary is machine-generated.

Lung transplantation is improving with expanded donor criteria, including donation after cardiac death (DCD) and ex vivo lung perfusion (EVLP). These advancements significantly increase donor lung utilization and transplant rates without compromising long-term outcomes.

More Related Videos

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Related Experiment Videos

Last Updated: May 10, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Area of Science:

  • Transplantation immunology
  • Thoracic surgery
  • Organ donation science

Background:

  • Lung transplantation is limited by donor organ scarcity.
  • Historical donor selection criteria restricted organ utilization.

Purpose of the Study:

  • To review recent advancements in lung donor selection, assessment, and management.
  • To highlight strategies increasing donor lung utilization.

Main Methods:

  • Review of expanded donor criteria, including donation after cardiac death (DCD) lungs.
  • Evaluation of ex vivo lung perfusion (EVLP) for donor lung assessment and improvement.
  • Analysis of outcomes using extended criteria donor lungs.

Main Results:

  • Donor lung utilization rates have increased from <15% to >50%.
  • Significant year-on-year increase in global lung transplants since 2004.
  • Intermediate-term studies show no significant compromise in long-term outcomes.
  • Extended criteria donor lungs do not yield significantly inferior results.

Conclusions:

  • Advancements in donor lung management and utilization are transforming lung transplantation.
  • Increased donor organ availability benefits patients with terminal lung disease.
  • Strategies developed for lung transplantation are being applied to other solid organs.