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Related Experiment Video

Updated: May 10, 2026

The Modified Temptation Resistance Task: A Paradigm to Elicit Children's Strategic Lie-telling

The Modified Temptation Resistance Task: A Paradigm to Elicit Children's Strategic Lie-telling

Published on: April 6, 2018

Truth under a masquerade!

Sarita R J Gonsalves¹, Geover Joslen Lobo, Norman Mendonca

¹Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India. gonsalvessarita@gmail.com

BMJ Case Reports

|July 4, 2013

Summary

This summary is machine-generated.

Bilateral orbital cellulitis, characterized by swelling and bulging eyes, can be an early indicator of widespread cancer metastasis in patients with a history of treated malignancies. This rare presentation highlights the importance of thorough investigation in recurrent or metastatic disease.

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Area of Science:

Oncology
Ophthalmology
Medical Imaging

Background:

A 32-year-old woman with a history of treated rectal adenocarcinoma presented with acute bilateral periorbital edema.
The patient had undergone surgery and chemotherapy six months prior, with initial negative metastasis workup.

Observation:

The patient rapidly developed bilateral axial proptosis, chemosis, and diminished vision within a week.
Examination revealed sluggish pupillary reactions and restricted extraocular movements. Systemic examination indicated poor nutritional status with elevated inflammatory markers.

Findings:

Computed tomography (CT) of the orbit and brain confirmed metastasis to the frontal bones and orbits.
Further investigations revealed concurrent liver and lung metastasis.

Implications:

This case underscores that bilateral orbital cellulitis can be an unusual presenting sign of systemic metastasis in patients with previously treated malignancies.
Prompt recognition and investigation are crucial for identifying advanced metastatic disease, even with seemingly localized symptoms.