Improving screening for cystic fibrosis-related diabetes at a pediatric cystic fibrosis program

Andrew S Kern1, Adrienne L Prestridge

  • 1Department of Otolaryngology-Head and Neck Surgery, The Wexner Medical Center at Ohio State University, Columbus, Ohio 60611-2605, USA. a-kern@fsm.northwestern.edu

Pediatrics
|July 4, 2013
PubMed

Insights

Screening rates for cystic fibrosis-related diabetes (CFRD) significantly improved after implementing a new outpatient system in a pediatric cystic fibrosis (CF) program. The initiative increased annual oral glucose tolerance test (OGTT) completion for eligible patients.

Area of Science:

  • Pediatric Endocrinology
  • Pulmonology
  • Quality Improvement in Healthcare

Background:

  • Guidelines recommend annual oral glucose tolerance tests (OGTT) for cystic fibrosis (CF) patients aged 10 years and older to screen for cystic fibrosis-related diabetes (CFRD).
  • Screening rates for CFRD were historically low at the pediatric CF center, indicating a gap in adherence to established guidelines.

Purpose of the Study:

  • To implement an effective, evidence-based outpatient screening system for CFRD within a pediatric CF program.
  • To improve the rate of annual OGTT screening for eligible CF patients.

Main Methods:

  • A systematic quality improvement initiative was developed, incorporating structured patient education, enhanced family communication, and streamlined laboratory appointment scheduling.
  • The primary outcome measured was the proportion of eligible patients receiving an OGTT by their subsequent clinic appointment.
  • Longitudinal tracking of the percentage of patients without CFRD who received an OGTT within the preceding 12 months was also conducted.

Main Results:

  • The outpatient screening rate for CFRD increased dramatically from 2% to 78% within 18 weeks post-implementation (P < .001).
  • Compared to the previous year, the screening rate also significantly improved from 35% to 78% (P < .001).
  • The overall percentage of patients without CFRD receiving a timely OGTT rose from 47% to 71% (P = .003).

Conclusions:

  • A systematic, quality improvement approach is effective in enhancing outpatient CFRD screening rates in pediatric CF programs.
  • The implemented system successfully addressed low screening rates, improving adherence to recommended guidelines for CFRD detection.
Abstract