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Updated: May 10, 2026

High-Throughput Measurement and Classification of Organic P in Environmental Samples
Published on: June 8, 2011
An expert system to predict the forced degradation of organic molecules
Alexis D C Parenty1, William G Button, Martin A Ott
1Lhasa Limited , 22-23 Blenheim Terrace, Woodhouse Lane, Leeds, LS2 9HD, United Kingdom.
Abstract:
In this paper we describe Zeneth, a new expert computational system for the prediction of forced degradation pathways of organic compounds. Intermolecular reactions such as dimerization, reactions between the query compound and its degradants, as well as interactions with excipients can be predicted. The program employs a knowledge base of patterns and reasoning rules to suggest the most likely transformations under various environmental conditions relevant to the pharmaceutical industry. Building the knowledge base is facilitated by data sharing between the users.
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