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Related Experiment Video

Updated: May 10, 2026

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
07:10

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain

Published on: March 13, 2020

Metals in wheat flour; comparative study and safety control.

Raquel L Tejera1, G Luis, Dailos González-Weller

  • 1Department of Toxicology, University of La Laguna, La Laguna, Tenerife, Canary Islands, Spain.

Nutricion Hospitalaria
|July 5, 2013
PubMed
Summary

This study analyzed twelve metals in wheat flour, finding that toxic elements like cadmium and lead contribute very little to the tolerable weekly intake, indicating the flour is safe for consumption.

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Area of Science:

  • Food Science
  • Analytical Chemistry
  • Toxicology

Background:

  • Wheat flour is a vital global commodity for the baking industry.
  • Ensuring the nutritional and toxicological safety of wheat flour is crucial.

Purpose of the Study:

  • To determine the content of twelve metals in wheat flour.
  • To assess the nutritional and toxicological safety of wheat flour samples.

Main Methods:

  • Analysis of macro elements (sodium, potassium, magnesium, calcium).
  • Analysis of micro elements (manganese, iron, copper, zinc, chrome, nickel).
  • Analysis of toxic trace elements (cadmium, lead).

Main Results:

  • Estimated daily intake for each metal was calculated.

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  • Contribution to the Recommended Daily Intake (RDI) and Provisional Tolerable Weekly Intake (PTWI) was determined.
  • Cadmium and lead contributions to PTWI were found to be very low.

    • Conclusions:

    • The analyzed wheat flour is safe concerning toxic metal content.
    • Wheat flour meets safety standards for both nutritional and toxicological aspects.