Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Longitudinal Research02:20

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Causes of Social Behavior III: Biological and Environmental Influences01:28

Causes of Social Behavior III: Biological and Environmental Influences

Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revitalizing the "biology" in "chronobiology".

Npj biological timing and sleep·2026
Same author

A cellular basis for the mammalian nocturnal-diurnal switch.

Science (New York, N.Y.)·2026
Same author

Reply to Maleszka et al.: DNA methylation signals persist across insect metamorphosis.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Multi-photon fluorescence-lifetime imaging of a genetically-encoded heme sensor.

Journal of inorganic biochemistry·2025
Same author

VacQuant: a tool to quantify neurodegeneration and associated vacuolation in brain tissue.

Fly·2025
Same author

Larval diapause slows adult epigenetic aging in an insect model, <i>Nasonia vitripennis</i>.

Proceedings of the National Academy of Sciences of the United States of America·2025

Related Experiment Video

Updated: May 10, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

Latitudinal clines: an evolutionary view on biological rhythms.

Roelof A Hut1, Silvia Paolucci, Roi Dor

  • 1Chronobiology unit, Centre for Behaviour and Neuroscience, University of Groningen, Groningen, The Netherlands. r.a.hut@rug.nl

Proceedings. Biological Sciences
|July 5, 2013
PubMed
Summary
This summary is machine-generated.

Circadian and annual timing systems show variations with latitude due to differing light and temperature patterns. Studying these latitudinal clines helps identify selection pressures on biological rhythms and discover new molecular components.

Keywords:
circadiancircannualdiapauselatitudephotoperiodreproduction

More Related Videos

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
10:38

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

Published on: September 27, 2012

Related Experiment Videos

Last Updated: May 10, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
10:38

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

Published on: September 27, 2012

Area of Science:

  • Chronobiology
  • Evolutionary Biology
  • Genetics

Background:

  • Circadian and annual timing systems are crucial for organismal adaptation.
  • Environmental factors like light and temperature vary with latitude, influencing these biological rhythms.
  • Latitudinal gradients present unique selective pressures on timing mechanisms.

Purpose of the Study:

  • To review literature on latitudinal clines in circadian phenotypes and clock gene polymorphisms.
  • To explore the association between these genetic variations and annual timing.
  • To discuss the utility of latitudinal clines in identifying selective forces on biological rhythms.

Main Methods:

  • Literature review focusing on studies examining latitudinal and altitudinal clines.
  • Analysis of research on circadian phenotypes and polymorphisms in circadian clock genes.
  • Synthesis of findings related to the adaptation of biological rhythms to different latitudes.

Main Results:

  • Evidence suggests systematic variations in circadian and annual timing with latitude.
  • Latitudinal clines in circadian clock gene polymorphisms are observed.
  • These variations are potentially linked to adaptation to local light and temperature regimes.

Conclusions:

  • Latitudinal clines are valuable tools for understanding the evolutionary forces shaping biological rhythms.
  • Studying these gradients can uncover novel molecular and physiological aspects of circadian and annual timing.
  • Geographic variation provides insights into the adaptive significance of timing systems.