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Updated: May 10, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
The challenge of prognostic markers in pleural mesothelioma
Andrea Imperatori1, Massimo Castiglioni, Lorenzo Mortara
1Center for Thoracic Surgery, Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy;
Abstract:
Malignant pleural mesothelioma (MPM) is a very aggressive tumor, highly resistant to chemo- and radio-therapy. Treatment of MPM patients is often disappointing, regardless of the modality used. Inter-individual variability of response to multimodal treatment remains a challenge and generally the MPM prognosis continues to be poor. Knowledge of predicting factors of outcome is currently insufficient; therefore, it would be highly desirable to find specific prognostic markers for MPM. Translational research projects are to be implemented.

