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Updated: May 10, 2026

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Published on: February 21, 2012

Scrub typhus.

Amy G Rapsang¹, Prithwis Bhattacharyya

¹Department of Anesthesiology and Intensive Care, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS) Campus, Shillong, Meghalaya, India.

Indian Journal of Anaesthesia

|July 5, 2013

Summary

Scrub typhus, an acute febrile illness, presents with fever and potential complications. Early diagnosis and treatment with doxycycline or azithromycin in pregnancy are crucial for favorable outcomes.

Keywords:

Doxycycline Weil-Felix test eschar orientia tsutsugamushi scrub typhus serologic assays tsutsugamushi disease

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Published on: August 31, 2013

Area of Science:

Infectious Diseases
Tropical Medicine
Public Health

Background:

Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi.
Transmission occurs through trombiculid mite bites, leading to vasculitis and end-organ injury.
Pregnancy cases are uncommon but linked to adverse fetal outcomes like fetal loss and preterm delivery.

Purpose of the Study:

To review the clinical presentation, diagnosis, and treatment of scrub typhus.
To highlight the specific considerations for scrub typhus in pregnant women and children.
To emphasize the importance of early diagnosis and prompt treatment to reduce complications.

Main Methods:

Literature search of MEDLINE/PubMed (1945-present).
Inclusion of studies on scrub typhus in children, pregnant women, and non-pregnant adults.
Keywords used: 'scrub typhus', 'pregnancy', 'children', 'complications', 'treatment'.

Main Results:

Scrub typhus presents with fever, headache, myalgia, cough, and gastrointestinal symptoms, potentially with an eschar.
Laboratory findings may include leukopenia, thrombocytopenia, and deranged hepatic/renal function.
Doxycycline is the recommended treatment; azithromycin showed favorable outcomes in pregnant women.

Conclusions:

Early diagnosis based on clinical suspicion and serologic confirmation is essential.
Prompt treatment with appropriate antibiotics, such as doxycycline, reduces mortality and complications.
Azithromycin is a safe and effective option for treating scrub typhus in pregnant women.