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Related Concept Videos

Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease I: Introduction01:25

Peptic Ulcer Disease I: Introduction

Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Jaundice01:25

Jaundice

Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...

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Granulocyte-dependent Autoantibody-induced Skin Blistering
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Psychogenic purpura.

Sharmila Sarkar1, Sudip Kumar Ghosh, Debabrata Bandyopadhyay

  • 1Department of Psychiatry, Calcutta National Medical College, Kolkata, West Bengal, India.

Indian Journal of Psychiatry
|July 5, 2013
PubMed
Summary

Psychogenic purpura, or Gardner-Diamond syndrome, is a rare skin condition causing bruising and bleeding, primarily in women with psychological distress. Early diagnosis is crucial for effective patient management and reduced healthcare costs.

Keywords:
Autoerythrocyte sensitization syndromeGardner-Diamond syndromepainful bruising syndromepsychogenic purpura

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Area of Science:

  • Dermatology
  • Psychiatry
  • Hematology

Background:

  • Psychogenic purpura, also known as Gardner-Diamond syndrome, is a rare cutaneous disorder.
  • It predominantly affects psychologically distressed adult women, presenting with recurrent ecchymotic lesions and bleeding.

Purpose of the Study:

  • To report a case of psychogenic purpura.
  • To highlight the importance of considering this rare condition in patients with recurrent ecchymoses.

Main Methods:

  • Case report presentation.
  • Literature review on psychogenic purpura and Gardner-Diamond syndrome.

Main Results:

  • The case illustrates the characteristic presentation of psychogenic purpura.
  • Emphasizes the diagnostic challenge due to its rarity.

Conclusions:

  • Early recognition of psychogenic purpura is vital.
  • Timely diagnosis can reduce extensive medical evaluations and improve patient outcomes.