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Primary thymic mucosa-associated lymphoid tissue lymphoma with multiple thin walled lung cysts: case report and
Lung-Yun Kang1, Szu-Pei Ho, Yi-Pin Chou
1Department of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, China.
Abstract:
Mucosa-associated lymphoid tissue (MALT) lymphoma of the thymus is rare. We reported a case of a 37-year-old Chinese female with Sjögren's syndrome and hyperglobulinemia. She suffered from chronic cough for 3 weeks. Chest computed tomography (CT) demonstrated a multiloculated cystic mass in mediastinum prevascular space and multiple lung cysts. Laboratory exam of autoimmune markers showed positive of antinuclear antibody (ANA), Sjögren's syndrome A (SSA), Sjögren's syndrome B (SSB), and rheumatoid factors (RF). Thymectomy with lymph node dissection was performed. The pathology report revealed thymic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue. Under immunohistochemical stains, CD20 and Bcl-2 were positive. No evidence of recurrence of disease was found.