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Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
A rare cause of hypocalcemia
Islam Y Elgendy1, Timi Rotimi Omokehinde
1Department of Medicine, University of Florida, Gainesville, FL, U.S.A.
The American Journal of Case Reports
|July 5, 2013
Summary
This case study highlights parathyroid hormone resistance as a rare cause of hypocalcemia. Familial causes should be considered after excluding more common reasons for low calcium levels.
Area of Science:
- Endocrinology
- Calcium Metabolism
Background:
- Serum calcium concentration is influenced by parathyroid hormone (PTH), vitamin D, ionized calcium, and phosphate.
- Disordered calcium metabolism can result from impaired PTH or vitamin D actions, including end-organ resistance to PTH.
Purpose of the Study:
- To report a case of hypocalcemia consistent with parathyroid hormone resistance.
Main Methods:
- Case report detailing a patient presenting with flu-like symptoms and incidental hypocalcemia.
Main Results:
- The patient's presentation was consistent with parathyroid hormone resistance.
Conclusions:
- Familial causes of hypocalcemia, though rare, warrant consideration after common causes are excluded.
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