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Related Experiment Video

Updated: May 10, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

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Published on: April 21, 2017

Pediatric Moyamoya disease.

Mohamed Nagiub¹, Iqbal Allarakhia

¹Department of Pediatrics, St. John Providence Children's Hospital, Detroit, Michigan, U.S.A.

The American Journal of Case Reports

|July 5, 2013

Summary

Moyamoya disease (MMD) is a rare cerebrovascular condition affecting children, particularly in East Asia. Early diagnosis through clinical evaluation and imaging, confirmed by conventional angiography, is crucial for effective management and surgical planning.

Keywords:

Moyamoya disease altered mental status familial MMD silent infarction

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Published on: June 22, 2022

Area of Science:

Neurology
Vascular Medicine
Pediatric Neurology

Background:

Moyamoya disease (MMD) is a progressive cerebrovascular occlusive disease affecting bilateral internal carotid arteries.
It causes a compensatory abnormal vascular network at the base of the brain.
MMD is the most common pediatric cerebrovascular disease in East Asia, with lower incidence in the USA.

Purpose of the Study:

To present a case of Moyamoya disease in a pediatric patient.
To highlight diagnostic considerations for MMD.

Main Methods:

Case report of a 7-year-old female presenting with transient altered mental status.
Diagnostic evaluation included history, physical examination, and brain imaging.
Conventional angiography was utilized for definitive diagnosis.

Main Results:

The patient was diagnosed with Moyamoya disease.
Conventional angiography confirmed the diagnosis and provided information for surgical planning.

Conclusions:

A high index of suspicion based on clinical presentation and imaging is key for diagnosing Moyamoya disease.
Conventional angiography is the gold standard for diagnosis and surgical planning in MMD patients.