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Updated: May 10, 2026

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Localized RNAi and Ectopic Gene Expression in the Medicinal Leech
Published on: April 17, 2008
A rare case of adverse effects caused by leech bite
Ugur Lok1, Selim Bozkurt, Mehmet Okur
1Department of Emergency, Adiyaman University, Adiyaman, Turkey.
The American Journal of Case Reports
|July 5, 2013
Summary
A 42-year-old woman experienced rare complications from a leech bite, including subcutaneous hematoma and skin reactions. This case highlights that Hirudo medicinalis can cause more than just external bleeding.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Hirudo medicinalis (medical leech) has historical and modern medical applications.
- Rare complications beyond external hemorrhage from leech bites are infrequently reported.
Purpose of the Study:
- To report an unusual clinical course and rare complications of a leech bite.
- To discuss cutaneous reactions and subcutaneous hematoma associated with Hirudo medicinalis.
Main Methods:
- Case report of a 42-year-old female patient presenting with painful, itchy lesions on lower extremities.
- Physical examination revealed erythematous, edematous, plaque-like lesions with central ecchymotic and hemorrhagic areas.
Main Results:
- The patient presented with extensive skin lesions and symptoms consistent with leech bites.
- The findings included regional subcutaneous hematoma and cutaneous reactions, which are not commonly reported.
Conclusions:
- Hirudo medicinalis can cause ecchymosis and diverse skin lesions, not limited to external bleeding.
- Physicians should consider leech bites in patients presenting with itchy lesions on the lower legs and feet.
- This case underscores the importance of recognizing uncommon leech bite complications.
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