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Primary aorto-enteric fistula - a unique complication of poorly differentiated large B-cell lymphoma

Oleg Shulik1, Kyle Marling, Jill Butler

  • 1Seton Hall University School of Health and Medical Sciences, Trinitas Regional Medical Center, Elizabeth, NJ, U.S.A.

The American Journal of Case Reports
|July 5, 2013
PubMed

Insights

Primary aorto-enteric fistula (PAEF) is a rare, life-threatening condition. This case highlights PAEF secondary to Large B-Cell Lymphoma, emphasizing the need for high clinical suspicion in cancer patients with aortic aneurysms.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Oncology

Background:

  • Primary aorto-enteric fistula (PAEF) is a rare and life-threatening condition involving communication between the aorta and gastrointestinal tract.
  • High mortality rates and delayed diagnoses are characteristic of PAEF.
  • While aortic abdominal aneurysms are common causes, cancer is an extremely rare etiology.

Purpose of the Study:

  • To report the first case of PAEF secondary to Large B-Cell Lymphoma.
  • To review the literature on malignant aorto-enteric fistulae.

Main Methods:

  • Case report presentation.
  • Comprehensive literature review.

Main Results:

  • Successful identification of PAEF secondary to Large B-Cell Lymphoma.
  • Compilation of existing knowledge on malignant aorto-enteric fistulae.

Conclusions:

  • Physicians must maintain a high index of suspicion for PAEF.
  • Consider PAEF in patients with unexplained anemia and a history of aortic abdominal aneurysm complicated by cancer.

Keywords:
aortoenteric fistulagastrointestinal hemmoragelymphoma

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