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Updated: May 10, 2026

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules
Published on: May 19, 2023
Detectability of simulated pulmonary nodules on chest radiographs: comparison between irradiation side sampling
Yuki Yano1, Hidetake Yabuuchi, Nobukazu Tanaka
1Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Objective:
To compare the detectability of simulated pulmonary nodules on chest radiographs between an irradiation side sampling indirect flat-panel detector (ISS-FPD) and computed radiography (CR).
Materials And Methods:
This study was an observer performance study. Simulated pulmonary nodules of 8 mm in diameter were superimposed on an anthropomorphic chest phantom. Chest radiographs were acquired under 2 exposure levels (4 and 3.2 mAs) with the ISS-FPD and the CR. Six thoracic radiologists evaluated all 40 images (10 patterns × 2 different exposure doses × 2 different systems) for the presence or absence of a lesion over each of 12 defined areas on a 3-megapixel monochrome liquid-crystal display. Receiver operating characteristic (ROC) curves were obtained for observation in predefined 480 areas. A jackknife method was used for statistical analysis. Differences with a P value of <0.05 were considered significant.
Results:
The analysis of the observer detection of simulated pulmonary nodules showed larger areas under the ROC curve (AUC) by the ISS-FPD than by the CR. There was a statistically significant difference between the two systems at 3.2 mAs (P=0.0330).
Conclusion:
The ISS-FPD was superior to the CR for the detection of simulated pulmonary nodules at 3.2 mAs.
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