Compensation of vertical vestibulo-ocular functions in squirrel monkeys after unilateral labyrinthectomy

Modifications in the vertical vestibulo-ocular reflex (VVOR) were studied in four squirrel monkeys (Saimiri sciureus) over time after unilateral labyrinthectomy. In the dark, with head upright, animals were exposed to sinusoidal rotation in the pitch plane. The magnetic field-pericorneal search coli technique was used to detect eye movement. The upward and downward slow-phase eye velocity (SPEV) of the VVOR and the maximum SPEV of the vertical component of spontaneous nystagmus (SPN) were studied. The mean preoperative gain of VVOR was symmetric. After unilateral labyrinthectomy, the maximum reduction of VVOR gain showed an asymmetry. The recovery of VVOR gain to the preoperative level took about 2 weeks, and the vertical component of SPN was present for about 3 weeks.