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[Plasmapheresis before thyroidectomy in a patient with thyrotoxicosis and hepatotoxicity by propylthiouracil: case
Ronald Freire de Almeida1, Ana Paula Comarella, Márcio Barcelos Silveira
1Serviço de Radiologia e Endocrinologia, Hospital Universitário Cassiano Antônio de Moraes, Universidade Federal do Espírito Santo (HUCAMUFES), Vitória, ES, Brasil.
Abstract:
Thyrotoxicosis is a rare clinical syndrome resulting from an exacerbation of hyperthyroidism, with various etiology and triggering factors. Its approach may be accomplished by blocking the synthesis of hormones, their secretion and/or inhibition of their peripheral action, besides treating the triggering factors. However, in refractory cases, plasmapheresis appears as an important option for treatment. We report a patient with Graves' disease who was admitted with thyrotoxicosis and signs of severe hepatotoxicity induced by propylthiouracil. Plasmapheresis was indicated, with the aim of rapidly reducing thyroid hormones in the preparation for total thyroidectomy.
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