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Trends in PCI volume after negative results from the COURAGE trial
1Department of Health Policy and Management, Emory University, Atlanta, GA.
Insights
Percutaneous coronary intervention (PCI) use decreased for stable angina patients after the COURAGE trial. Comparative effectiveness research influenced practice, though some patients still receive PCI.
Area of Science:
- Cardiovascular Medicine
- Health Services Research
- Interventional Cardiology
Background:
- The COURAGE trial demonstrated medical therapy's equivalence to percutaneous coronary intervention (PCI) for stable angina.
- Post-trial, understanding shifts in PCI utilization for stable versus acute coronary syndromes is crucial.
Purpose of the Study:
- To analyze trends in PCI volume following the COURAGE trial publication.
- To differentiate PCI trends based on patient diagnosis: stable angina versus acute myocardial infarction (AMI) or unstable angina.
Main Methods:
- Utilized comprehensive inpatient and outpatient discharge data from Florida, Maryland, and New Jersey.
- Incorporated data from the English Hospital Episode Statistics database for international comparison.
- Examined PCI volumes before and after the COURAGE trial across different diagnostic categories.
Main Results:
- PCI use for stable angina in the US (FL, MD, NJ) decreased by 17% from 2006 to 2008.
- No significant change in PCI volume was observed for patients with AMI.
- Similar PCI trend declines were noted in US community hospitals, but not in England.
Conclusions:
- The COURAGE trial's findings appear to have influenced US practice, leading to reduced PCI for stable angina.
- Comparative effectiveness research can drive cost-saving practice pattern changes.
- A notable number of patients with stable coronary disease continue to undergo PCI despite trial evidence.
Objective:
To describe trends in the use of percutaneous coronary intervention (PCI) following the COURAGE trial, which found that medical therapy is as effective as PCI for patients with stable angina.
Data Sources:
We used the National Hospital Discharge Survey; inpatient and outpatient discharge data from Florida, Maryland, and New Jersey; and the English Hospital Episode Statistics database.
Study Design:
We report trends in PCI volume by diagnosis (stable angina vs. unstable angina or AMI) before and after publication of the COURAGE trial.
Principal Findings:
The number of PCIs in patients without a diagnosis of AMI or unstable angina in Florida, Maryland, and New Jersey declined from 48,000 in 2006 to 40,000 in 2008 (-17 percent). There was no change in the number of PCIs in patients with a diagnosis of AMI. We observed similar patterns in U.S. community hospitals. PCI volume did not decline in England.
Conclusions:
PCI volume declined after publication of the COURAGE trial. The experience of the COURAGE trial suggests that comparative effectiveness research can lead to cost-saving changes in medical practice patterns. However, there are many patients with stable coronary disease who continue to receive PCI post-COURAGE.
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