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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Related Experiment Video

Updated: May 10, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Seasonal allergic rhinitis.

Alexander K C Leung1, Kam-Lun E Hon

  • 1Department of Pediatrics, The University of Calgary, Alberta Childrens Hospital, Calgary, Alberta, Canada. aleung@ucalgary.ca

Recent Patents on Inflammation & Allergy Drug Discovery
|July 9, 2013
PubMed
Summary
This summary is machine-generated.

Seasonal allergic rhinitis management involves allergen avoidance and pharmacotherapy. Options range from antihistamines and corticosteroids for mild cases to immunotherapy for severe or persistent symptoms.

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Area of Science:

  • Allergy and Immunology
  • Otolaryngology

Background:

  • Seasonal allergic rhinitis presents with symptoms like rhinorrhea, nasal congestion, itching, and sneezing.
  • Allergen avoidance is the primary management strategy.

Purpose of the Study:

  • To review current pharmacotherapy options for seasonal allergic rhinitis.
  • To identify patient candidates for immunotherapy.
  • To discuss recent patents in the field.

Main Methods:

  • Literature review of pharmacotherapy for seasonal allergic rhinitis.
  • Analysis of criteria for immunotherapy referral.
  • Review of recent patent literature.

Main Results:

  • Mild to moderate cases respond well to oral/intranasal second-generation antihistamines or intranasal corticosteroids.
  • Severe cases may necessitate combination therapy, including intranasal corticosteroids.
  • Immunotherapy is indicated for patients with persistent symptoms, multiple affected seasons, or adverse drug reactions.

Conclusions:

  • Pharmacotherapy effectively manages symptoms and improves quality of life for most patients.
  • Treatment selection depends on symptom severity and patient-specific factors.
  • Immunotherapy offers a long-term solution for select patient populations.